Phumeza Tisile knows the struggles of being infected with XDR-TB and wants to make sure no other suffers from it. (Image: Doctors Without Borders)Proper diagnosis of disease is critical as this gives the framework for the treatment and medication needed. A wrong diagnosis can be fatal; thankfully for Phumeza Tisile, it was not.Tisile was only 19 years old in 2010 when she was diagnosed with tuberculosis (TB). She was, however, misdiagnosed: in reality, she was ill with extensively drug-resistant TB (XDR-TB), the deadliest form of the disease.Sufferers of XDR-TB go through an excruciating two-year journey during which time they must swallow up to 20 pills a day. They must also receive a painful injection every day for the first eight months, making it hard to sit or even lie down. For many, the treatment makes them feel sicker than the disease itself, as side effects cause nausea, body aches and rashes.Because of her misdiagnosis, Tisile reacted badly to the drugs she was prescribed. She lost her hearing and had to have surgery on her lungs.Her lifeline came in the form of Jennifer Hughes, a TB doctor from Doctors Without Borders, at the Cape Town clinic where she was being treated. Following their chance encounter, Hughes drew up an individualised treatment regimen for the young woman.Linezolid was part of her treatment. Linezolid was not developed to treat TB specifically; rather it is an antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to other antibiotics. The main uses are to fight infections of the skin and pneumonia, and because of patent issues it is very expensive.Tisile was cured in 2013, but she began her fight against disease by writing a manifesto – with the support of Hughes – to get support from doctors and patients in overcoming XDR-TB.THE MANIFESTOTest Me Treat Me, Tisile’s manifesto, calls for three things in particular:Everyone must have access to testing and treatment for XDR-TB;There needs to be better treatment and higher cure rates; and,The international community must fund the fight against XDR-TB.Tisile told Redbull Amaphiko, a collaborative platform for social entrepreneurs who want to bring change to the world: “The reason we wrote the manifesto was to let the world health leaders know that XDR-TB was an emergency.”After presenting it to the World Health Assembly in Geneva in May 2014, she described it as a “20-year strategy”. “Besides handing over the manifesto, I did interviews with health journalists from Germany and wrote a blog on The Guardian. There were workshops organised by Doctors Without Borders where I spoke about my experience with TB,” said Tisile of her experience in Switzerland.CHEAPER DRUGS THE SOLUTIONDuring her three years of treatment, Tisile was part of a privileged 20 out of 300 suffering from XDR-TB to be treated with Linezolid.“It’s because of the patent laws,” she explained. “The drug is too expensive and people who need it the most can’t get it. I’ve met people who I called friends who have now died.”Linezolid is sold at R700 a tablet, but Tisile says there is a cheaper version from India that costs R20 a tablet.PREACHING THE CURETisile, who is now 24 years old, lost her hearing as a result of the misdiagnosis, but since then has had two cochlear implants and has regained her hearing. Her journey to recovery has given her the opportunity to speak about her story to medical students and ordinary people as part of TB Proof.TB Proof is a grassroots health care and TB survivor initiative founded in 2012 by South African Health Care Workers and Students after multiple personal experiences with occupational tuberculosis, particularly multidrug-resistant TB.Since working with TB Proof, Tisile said, she had learnt that medical students, professional nurses and doctors did not wear TB masks when attending to patients because they feared their colleagues would see them as weak.
Share Facebook Twitter Google + LinkedIn Pinterest DuPont (NYSE:DD) and The Dow Chemical Company (NYSE:DOW) announced the U.S. site structure for the global agriculture leader the companies intend to create following the planned separation of DowDuPont into three independent, publicly traded companies.The corporate headquarters for the Agriculture company will be located in Wilmington, Delaware and will include the office of the CEO and key corporate support functions. Sites in Johnston, Iowa and Indianapolis, Indiana will serve as Global Business Centers, with leadership of business lines, business support functions, R&D, global supply chain, and sales and marketing capabilities concentrated in the two Midwest locations. In addition, the independent Agriculture company will feature DuPont in the company’s name, following completion of the corporate naming and branding process.“This efficient structure takes full advantage of the unique expertise and resources that exist in each location, enabling us to deliver the long-term opportunity for the leading global Agriculture company we intend to create,” said Edward D. Breen, chairman and chief executive officer of DuPont. “Our deep presence in Iowa and Indiana will continue the close ties to our customer base and the broader Agriculture community, while leveraging the existing corporate infrastructure and expertise we have in Delaware — DuPont’s home for more than 200 years.”The structure of the Agriculture company was specifically developed to ensure the cost discipline and efficiency necessary to achieve the previously stated $1.3 billion in synergies, while establishing the strongest foundation possible for sustainable growth over the long term — which will in turn create long-term opportunities for the company’s global employee base and local communities. This structure enables the intended independent Agriculture company to consolidate DuPont’s and Dow’s complete Agriculture capabilities across seed and crop protection in three primary locations, which is integral to achieving the planned synergies.“We want to thank the leaders of each state for a highly constructive, cooperative process to achieve the best possible approach that leverages key advantages in each location. As we advance plans for the intended merger, DuPont and the state of Delaware are committed to leveraging our respective science infrastructures and competencies to nurture the emerging science and technology innovation hub in the state,” Breen said.“The proposed combination of Dow’s and DuPont’s agricultural businesses will create a U.S.-based global leader with the scale and breadth necessary to deliver greater value and choice for growers worldwide and compete against the largest global competitors,” said Andrew N. Liveris, chairman and chief executive officer of Dow. “Combining each company’s strengths in science and R&D, with increased global market access, enables greater opportunity for innovative new solutions in both seed and crop protection. The headquarters location of the Agriculture company being announced as Wilmington, with global business centers in Indiana and Iowa is consistent with the intended headquarters of the Material Science company, to be named Dow, being headquartered in Midland, Michigan, but having global business centers in other U.S. and global locations.”“Today’s announcement is another step toward our creation of a leading global agriculture company. The intended Agriculture company will be highly focused, stronger, more competitive, more resilient and better equipped to deliver growth and long-term, sustainable value than either DuPont or Dow could deliver on its own. Both companies have highly respected brands in the agriculture industry, such as Pioneer and Mycogen, which we will continue to build and leverage. Going forward, we will be better equipped to meet and exceed grower expectations for innovation in crop technology and agricultural services. We intend to bring a broader suite of products to the market, faster, to increase grower productivity and profitability,” Breen concluded. With the announcement of the intended Agriculture company site structure, each headquarters location of the three intended independent, publicly traded companies now has been determined.Agriculture Company: A leading global pure‐play Agriculture company that unites the Seeds and Crop Protection businesses from DuPont and Dow. The combined entity is expected to have the most comprehensive and diverse portfolio in the industry and a robust pipeline with exceptional growth opportunities in the near‐, mid‐ and long‐term. The complementary offerings will provide growers across geographies with a broad portfolio of solutions and greater choice. The Agriculture company will be headquartered in Wilmington, Delaware. In addition, the independent Agriculture company will feature DuPont in the company’s name.Material Science Company: A pure‐play industrial leader, consisting of Dow’s Performance Plastics, Performance Materials and Chemicals, Infrastructure Solutions, Consumer Care and Automotive Solutions (excluding the Dow Electronic Materials business) operating segments, as well as DuPont’s Performance Materials segment. The combination of complementary capabilities is expected to create a low‐cost, innovation‐driven leader that can provide customers in high‐growth, high-value industry segments in packaging, transportation, and infrastructure solutions, among others, with a broad and deep portfolio of cost‐effective offerings. The Material Science company will be headquartered in Midland, Michigan. In addition, the independent Material Science company will feature Dow in the company’s name.Specialty Products Company: A leading global specialty business focused on attractive secular growth markets where innovative science capabilities offer a clear competitive advantage. The company is expected to be composed of four strong businesses which include DuPont’s Nutrition & Health, Industrial Biosciences, and Protective Solutions businesses as well as the integration of DuPont’s Electronics & Communications business with Dow’s Electronic Materials business unit. The Specialty Products company will be headquartered in Wilmington, Delaware.Prior to the intended separation into three independent companies, DowDuPont will be dual headquartered in Wilmington, Delaware and Midland, Michigan.Both parties continue to plan for the closing of the transaction during the second half of 2016, subject to satisfying the necessary closing conditions including obtaining the required pre-merger regulatory approvals.
Share Facebook Twitter Google + LinkedIn Pinterest Two new AutoTrac products are available to help row crop producers and ag service providers more accurately navigate row-crop fields when making postemergence sprayer applications.AutoTrac Vision utilizes a single-lens camera to detect crop rows and help steer the sprayer down the center of the row for early postemergence applications. AutoTrac RowSense uses a row sensor similar to that used on combines to detect crop rows and steer the sprayer to the center of the row for later season post applications.Doug Felter, product marketing manager for John Deere, says the introduction of these two new AutoTrac guidance products is designed to help large-scale row-crop producers and ag service providers work more quickly, cover more acres and reduce run-over damage to crops when spraying in the fields.“Because of field terrain, planter drift, or irregular planting without guidance, spraying in row crops can present challenges for sprayer operators making post emerge applications,” Felter explains. “These two new guidance applications help sprayers track more accurately between the rows, resulting in reduced crop damage, less operator fatigue and more effective field applications.”New AutoTrac Vison uses a monocular camera mounted on the front of the sprayer to detect crop rows and to steer the vehicle between the rows for early season postemerge applications. It is currently approved for use in corn, soybeans and cotton planted in 30-inch rows starting when the crop is at least 6 inches tall. It can be used until there is at least 3 inches of soil showing between rows or up to 90 percent canopy closure.AutoTrac RowSense uses a sensor paddle mounted on the sprayer wheel to detect crop rows and to help steer the machine down the center of the row. Designed to be used later in the growing season, RowSense is currently approved for use in corn at least 4 feet tall planted in 30-inch rows.“While these two sprayer guidance systems are completely separate and are to be used one at a time, both have performed well in a variety of field conditions and crops,” Felter adds. “Both automated vehicle steering systems allow the operator to spray at faster speeds with little manual steering and cover more acres per day with less damage to crops.”Both systems are available as field-installed kits on currently operating machines or from the factory on new John Deere R4023, R4030, R4038 and R4045 Sprayers. A GS3 AutoTrac RowSense activation is required.For more information on the new John Deere AutoTrac Vision and RowSense sprayer guidance systems for 4 Series Sprayers, contact your local John Deere dealer or visit JohnDeere.com/ag.Deere & Company (NYSE: DE) is a world leader in providing advanced products and services and is committed to the success of customers whose work is linked to the land – those who cultivate, harvest, transform, enrich and build upon the land to meet the world’s dramatically increasing need for food, fuel, shelter and infrastructure. Since 1837, John Deere has delivered innovative products of superior quality built on a tradition of integrity. For more information, visit John Deere at its worldwide website atwww.JohnDeere.com.
Sign up for a free trial and get instant access to this article as well as GBA’s complete library of premium articles and construction details. A surprising number of people don’t understand the causes of condensation. If you ask a stranger on the sidewalk, “Does condensation happen when cold air encounters a warm surface, or when warm air encounters a cold surface?,” many people will shrug their shoulders.Here’s an example of this type of confusion: When drivers see condensation on their windshield during the summer, they are often unsure of the best remedy. Should they turn on the heater or the air conditioner?Let’s look at four different scenarios.This is the most common type of cold-weather condensation on a windshield.Where did the moisture come from? The moisture came from the outdoor air.What’s the cause? Due to night-sky radiation, the temperature of the windshield dropped below the dew point of the outdoor air.What’s the solution? If all you have is dew, you can jump in the car and use the windshield wipers. If you have frost on your windshield, you either have to scrape the outside of the windshield, or let your engine idle for a while so that the engine coolant gets warm enough to provide heat through your defroster vents.This phenomenon only happens when all of the vehicle’s windows are closed. It occurs more rarely than exterior condensation.Where did the moisture come from? The moisture came from the air inside the vehicle.What’s the cause? This phenomenon happens when the interior of the vehicle is very damp (as might occur if the carpeting has been soaked by melted snow from the driver’s boots). At night, the outdoor temperature drops below the temperature of the air inside the car, and the windshield is chilled by the outdoor air (even on a night without significant night sky radiation). The temperature of the windshield… This article is only available to GBA Prime Members Start Free Trial Already a member? Log in