Global LAG-3 Antagonist Pipeline Insight Report 2021: Emerging Drugs Include Tebotelimab (MacroGenics) & LAG525…

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Key PlayersMacroGenicsNovartisMerck Sharp & DohmeCrescendo BiologicsF-star TherapeuticsMICROBIO GroupBristol-Myers SquibbOno PharmaceuticalsSymphogenAvactaAbeome Corporation Key PlayersTebotelimabLAG525FavezelimabCB213FS-118SNA-03RelatlimabSym022AVA-0017LAG3 antagonist For more information about this drug pipelines report visit https://www.researchandmarkets.com/r/pa9rkx View source version on businesswire.com:https://www.businesswire.com/news/home/20210216005575/en/ CONTACT: ResearchAndMarkets.com Laura Wood, Senior Press Manager [email protected] For E.S.T Office Hours Call 1-917-300-0470 For U.S./CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 KEYWORD: INDUSTRY KEYWORD: HEALTH PHARMACEUTICAL SOURCE: Research and Markets Copyright Business Wire 2021. PUB: 02/16/2021 05:10 AM/DISC: 02/16/2021 05:10 AM http://www.businesswire.com/news/home/20210216005575/en By Digital AIM Web Support – February 17, 2021 Twitter Facebook DUBLIN–(BUSINESS WIRE)–Feb 16, 2021– The “LAG-3 Antagonist – Pipeline Insight, 2021” drug pipelines has been added to ResearchAndMarkets.com’s offering. This “LAG-3 Antagonist – Pipeline Insight, 2021,” report provides comprehensive insights about 20+ companies and 20+ pipeline drugs in LAG-3 Antagonist pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. Report HighlightsThe companies and academics are working to assess challenges and seek opportunities that could influence LAG-3 Antagonist R&D. The therapies under development are focused on novel approaches for LAG-3 Antagonist.On 5th May 2020 Crescendo Biologics and Cancer Research announced a Clinical Development Partnership to progress one of Crescendo’s novel bispecific Humabody immunotherapies, CB213, into clinical trials targeting cancers of high unmet medical need. Under the terms of the agreement, Cancer Research UK’s Centre for Drug Development will sponsor and fund a future Phase I clinical trial for CB213, in patients with solid tumors. LAG-3 Antagonist Emerging Drugs Chapters This segment of the LAG-3 Antagonist report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases. LAG-3 Antagonist Emerging DrugsTebotelimab: MacroGenics Tebotelimab (previously known as MGD013) is an investigational, first-in-class bispecific, tetravalent DART molecule targeting PD-1 and LAG-3. Tebotelimab has been engineered to bind PD-1 and LAG-3 concomitantly or independently and disrupt these non-redundant inhibitory pathways to further restore exhausted T-cell function.LAG525: Novartis LAG525, also known as IMP701 is an investigational molecule being developed to potentially treat a range of solid tumors. It is a high-affinity, ligand-blocking, humanized anti-LAG-3 IgG4 antibody which blocks the binding of the known LAG-3 ligand MHC class II to LAG-3. Immutep began the development of LAG525 and is now being continued by Novartis in collaboration with the Australian biotechnology company Prima BioMed. LAG-3 Antagonist: Therapeutic Assessment This segment of the report provides insights about the different LAG-3 Antagonist drugs segregated based on following parameters that define the scope of the report, such as: Major Players working on LAG-3 Antagonist There are approx. 20+ key companies which are developing the LAG-3 Antagonist. The companies which have their LAG-3 Antagonist drug candidates in the most advanced stage, i.e. Phase II/III include, Bristol-Myers Squibb/Ono Pharmaceuticals. The report covers around 20+ products under different phases of clinical development likeLate-stage products (Phase III andMid-stage products (Phase II andEarly-stage products (Phase I/II and Phase I) along with the details ofPre-clinical and Discovery stage candidatesDiscontinued & Inactive candidatesRoute of Administration LAG-3 Antagonist pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such asInfusionIntradermalIntramuscularIntranasalIntravaginalOralParenteralSubcutaneousTopicalMolecule Type Products have been categorized under various Molecule types such asVaccinesMonoclonal AntibodyPeptidesPolymerSmall moleculeProduct Type The drugs have been categorized under various product types like Mono, Combination and Mono/Combination. LAG-3 Antagonist: Pipeline Development Activities The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses LAG-3 Antagonist therapeutic drugs key players involved in developing key drugs. Pipeline Development Activities The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging LAG-3 Antagonist drugs. LAG-3 Antagonist Report Insights Pinterest WhatsApplast_img read more