Stand Up To Cancer creates Dream Team focused on finding therapies for

first_img Source: Reviewed by James Ives, M.Psych. (Editor)Jan 29 2019Stand Up To Cancer announced here today the creation of an $8 million Dream Team of top scientists focused on finding therapies for T-cell lymphoma, a rare cancer of the blood and immune system, using chimeric antigen receptors (CARs) to trigger the immune system to attack and destroy cancerous cells.The SU2C Meg Vosburg T-Cell Lymphoma Dream Team: Tailoring CAR-based Immunotherapy Strategies to T-cell Lymphoma will be headed by Helen Heslop, MD, Baylor College of Medicine (BCM), with Gianpietro Dotti, MD, University of North Carolina Chapel Hill (UNC-CH), as co-leader. The team honors the memory of Meg Vosburg, a lifelong learner, educator, and humanitarian, who died from T-cell lymphoma in 2018 at the age of 51.The announcement came at the annual SU2C Scientific Summit, a gathering of more than 400 scientists and SU2C supporters organized by the American Association for Cancer Research, SU2C’s Scientific Partner, and held at the Loews Santa Monica Beach Hotel.The challenge in developing immunotherapy to treat T-cell lymphoma has been finding a therapy that attacks cancerous T cells without harming cells which are essential to the body’s immune response.”We’re exploiting the potential of the immune system to cure T-cell lymphoma by genetically modifying immune system cells, called T cells, so they have new receptors that will allow them to recognize the lymphoma cells and kill them,” Heslop said. “And we’re evaluating several different targets and several different sorts of immune effector cells. It’s a modular sort of system where we can hopefully combine the best from each different approach to produce a therapy that will improve outcomes in this patient population.”In addition, the team is working to modify the CAR-carrying cells so that they are not hindered by immune cells. This will help reduce the cancer and prepare patients for potential stem cell transplants to contain or cure the cancer.CAR therapy is usually custom-built for each patient. The team is trying to find a way to develop CAR cells on an “off-the-shelf” basis so the therapy will be more available to patients and less expensive. The team is also working to identify biomarkers that will help track the effectiveness of the therapy, and is evaluating a novel small molecule which shows encouraging activity in T-cell lymphoma as a cytoreductive (size-reducing) regimen.Heslop is Dan L Duncan chair and director of the Center for Cell and Gene Therapy at BCM, Houston Methodist Hospital, and Texas Children’s Hospital. She is a professor in the hematology-oncology section of the Departments of Medicine and Pediatrics at BCM in Houston and is also associate director for clinical research and leader of the Cancer Cell and Gene Therapy Program at Baylor’s Dan L Duncan Comprehensive Cancer Center.Dotti is director of the immunotherapy program at the University of North Carolina (UNC) Lineberger Comprehensive Cancer Center and professor in the Department of Microbiology and Immunology at UNC-CH.T-cell lymphomas make up less than 15 percent of non-Hodgkin lymphomas in the United States, according to the American Cancer Society, and they tend to be difficult to treat because they arise in the cells that are supposed to fight disease, not cause it.Related StoriesNew shingles vaccine reduces outbreaks of painful rash among stem cell transplant patientsStudy reveals link between inflammatory diet and colorectal cancer riskNanoparticles used to deliver CRISPR gene editing tools into the cell”We are proud to extend SU2C’s work into T-cell lymphoma,” said Phillip A. Sharp, PhD, the Nobel Prize-winning molecular biologist from MIT who serves as chair of the SU2C Scientific Advisory Committee. “The Dream Team’s approach could bring a highly effective new treatment to what is now a relatively intractable disease.”Other scientists on the team include:Baylor College of Medicine: Malcolm K. Brenner, MD, PhD, investigatorCarlos Ramos, MD, investigatorMaksim Mamonkin, PhD, young investigatorLaQuisa Hill, MD, young investigatorRayne Rouce, MD, young investigatorNatasha Lapteva, PhD, investigatorUniversity of North Carolina-Chapel Hill:Barbara Savoldo, MD, PhD, investigatorAnne Beaven, MD, investigatorNatalie Grover, MD, young investigatorJoel Parker, PhD, investigatorPaul Eldridge, PhD, investigatorThe University of Texas MD Anderson Cancer Center (MDACC)Katy Rezvani, MD, PhD, Dream Team principalElizabeth J. Shpall, MD, investigatorMay Daher, MD, young investigatorWake Forest Baptist Health Comprehensive Cancer Center (WFBHCCC):Bayard Powell, MD, Dream Team principalTimothy S. Pardee, MD PhD, investigatorWei Zhang, PhD, investigatorZanetta S. Lamar, MD, young investigatorAdvocatesPatty Spears, UNC Lineberger Patient Research Advocacy Group.Gustavo Ayala, MD, University of Texas in Houston; parent of a teenager with T-cell lymphoma.Bambi Grilley, director of Clinical Research and Early Product Development at Cell and Gene Therapy at BCM.Ruth Sorelle, retired journalist and survivor of NK-T cell lymphoma.Cancer immunotherapy – enabling the body’s immune system to detect and destroy cancer cells — has had a tremendous impact on a wide range of cancers, including B-cell lymphomas. However, it has not yet been effective in lymphomas that involve T cells. The biggest problem is finding a therapy that can attack T cells that are cancerous while leaving normal T cells alone, since T cells are essential to the body’s immune response.The Dream Team will test therapeutic approaches that utilize cells to carry molecules known as CARs against different antigens that are found on the surface of cancerous T cells. Knowing the most effective combination of immune cell effectors and CARs will allow scientists to develop CAR-based therapeutics where the patient’s own immune system can expand into armies of cancer-fighting cells.”It’s been just over a year since Meg’s diagnosis,” remarked her husband, Craig Vosburg, “and I’m excited to hear about the new ideas to help patients in the foreseeable future as a result of this Dream Team.””Meg had a passion for making people’s lives better, which she did through education and helping them find ways to pursue their dreams,” he said. “What better way to continue doing that than by extending lives and someday finding a cure for future patients diagnosed with this difficult disease.”last_img read more

Kimia Lab and Huron participate in 126 million Industry Consortium for Image

first_imgJun 6 2019University of Waterloo’s Kimia Lab announced today that it will participate in the $126 million Industry Consortium for Image Guided Therapy (ICIGT) led by the Sunnybrook Research Institute, with investment partnership from the Canadian government. The Canadian government, through its Strategic Innovation Fund, will invest up to $49 million to support the ICIGT initiative, which, in addition to Kimia Lab and Huron Digital Pathology, consists of more than 70 partners from industry, academia, government organizations and not-for-profits.Related StoriesIT Faces the Digital Pathology Data TsunamiHuron announces collaboration with UPMC and abstract presentation at Pathology Informatics SummitNeurohistology: how whole slide scanning impacts workflowThe consortium’s mandate is to accelerate the application of artificial intelligence and machine learning technologies to deliver better health outcomes, faster diagnoses and safer treatments that minimize side effects and the length of hospital stays.Kimia and Huron’s project within ICIGT aims to develop intelligent algorithms for consensus building and auto-reporting in digital pathology to improve the speed, cost and accuracy of diagnosis. Huron, in technical partnership with the Kimia Lab, recently introduced the world’s first image search engine that connects pathologists to the vast knowledge contained in the world’s pathology reports. This is a historic opportunity to initiate a major change in diagnostic pathology. The AI-driven auto-reporting will be the main output of the project enabling diagnostic consensus by accessing large archives of histopathology images and learning from evidently diagnosed cases of the past.”Professor Hamid Tizhoosh, Director of Kimia Lab at University of Waterloo Source: Huron Digital Pathology With this project we will develop and bring to market novel technology that addresses a severe shortage of pathologists in Canada and around the world. Together with our fellow ICIGT members, and with support from the Canadian government, we are further positioning Canada as a world leader in leading-edge medical technologies.”Patrick Myles, CEO of Huron Digital Pathologylast_img read more

A million a day STIs are a worldwide epidemic declares WHO

first_img Gonorrhea 26/td> 20 Syphilis 1.6 1.7 STI Incidence/1000 (men) Incidence/1000 (women) Trichomoniasis 42 40 Image Credit: Shubin Vitaliy / Shutterstock Estimates are that 1 in 25 people the world over have one or more STIs. But many of them may not even know it because of the lack of symptoms, which means they don’t seek treatment but spread it to others.This includes 87 million cases of gonorrhea, 6.3 million of syphilis, 127 million cases of chlamydia and 156 million of trichomoniasis. Strikingly, these high figures do not even touch upon STIs like herpes, HIV and HPV infection, which will be published in a few months. Both high- and low-income regions of the world are equally affected though STI patterns vary.The estimated incidence figures are represented as a table below. Why bother about STIs?Untreated, these STIs can devastate the body, causing problems ranging from chronic neurological and cardiovascular disease, infertility and tubal pregnancies, to stillbirths and an increased risk of acquiring HIV infection. For instance, one of the biggest baby killers in 2016 was syphilis, which caused 200,000 babies to be born lifeless or to die soon after birth. They also disrupt homes, causing domestic violence and social ostracism.Study author Melanie Taylor says: “”We consider this a hidden epidemic, a silent epidemic, a dangerous epidemic.” Its impact is bitter, she says, labeling it “persistent within populations, families and relationships and quite damaging to all.”STIs spread primarily via sexual activity. Other routes include vertical spread (from mother to child, during pregnancy or delivery), through infected blood/blood products (as with syphilis), and hypodermic sharing for injected drug abuse.People don’t bother to make sure they are protected from STIs, say WHO experts like Teodora Wi, who warns: “Sexually transmitted infections are everywhere. They are far more common than we think.”With the fear of HIV lessening, due to effective preventive pills and treatments, people have become “complacent about protection”, says Wi, despite the universal availability of sex with unknown partners today – a truly dangerous trend.Incurable STIs?Treatment of STIs is relatively simple and the drugs are typically easily available, except for benzathine penicillin, a long-acting form of the drug used to treat syphilis. However, the high number of gonorrhea cases is frightening, because “super-gonorrhea” has cropped up in some places, showing resistance to multiple antibiotics. Experts fear that this may become increasingly common, making the disease incurable.Drug resistance is also being found with other STIs, like Mycoplasma genitalium and syphilis. Tim Jinks, drug-resistance expert at Wellcome, warned, “Untreatable cases of gonorrhoea are harbingers of a wider crisis where common infections are harder and harder to treat. We urgently need to reduce the spread of these infections and invest in new antibiotics and treatments to replace those that no longer work.”Urgent action against STI spreadTo reduce this alarming figure, WHO recommends making STI testing affordable and accessible, promoting STI screening among those who are sexually active, and setting up screening programs for syphilis and HIV in all pregnant women.Wi opposes recent budget cuts that affect STI testing and control in many countries, calling on policymakers to increase the spending on sexual health instead.WHO research on STIs is based mostly on figures from women, and prevalence data is limited. It is trying to improve global and national data collection and surveillance. Prevention efforts, better health care for those with STIs, point-of-care diagnostic kits, improved treatment strategies, and vaccine development are among the target areas.The report was published on June 6, 2019, in the Bulletin of the World Health Organization. In the overwhelming majority of cases, STIs are not only curable but highly preventable. Proper sex education and consistent correct condom use with every act of sex between new or casual partners, including oral, anal and vaginal intercourse, is known to prevent the spread of STIs.All the same, STIs continue to rise, with no change in existing or new infection rates from 2012.Peter Salama, WHO executive director for universal health coverage, called this “a concerning lack of progress” and “a wake-up call for a concerted effort to ensure everyone, everywhere, can access the services they need to prevent and treat these debilitating diseases.” Chlamydia 33< 34 What is an STD (Sexually Transmitted Disease)? STD Pathophysiology STD Prevention and Treatment STD Diagnosis Further Reading By Dr. Liji Thomas, MDJun 6 2019STIs continue to rise globally, with more than 1 million new STIs of just four types being reported every day, according to a new report from the World Health Organization (WHO). This comes to over 376 million new STIs a year among people between 15 and 49 years. Source:Rowley, J. et al., (2019). Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016.  Bulletin of the World Health Organization, and read more

Postmenopausal women may be healthier if more pearshaped than appleshaped

first_img“Our findings suggest that postmenopausal women, despite having normal weight, could have varying risk of cardiovascular disease because of different fat distributions around either their middle or their legs. In addition to overall body weight control, people may also need to pay attention to their regional body fat, even those who have a healthy body weight and normal BMI,” Dr Qibin Qi, an associate professor at the Albert Einstein College of Medicine, New York (USA), said in a statement. “However, it is important to note that participants of our study were postmenopausal women who had relatively higher fat mass in both their trunk and leg regions. Whether the pattern of the associations could be generalizable to younger women and to men who had relatively lower regional body fat remains unknown,” Dr. Qi added. Image Credit: Aleksandar Todorovic / Shutterstock By Angela Betsaida B. Laguipo, BSNJul 2 2019Apple-shaped women are three times more likely to have a heart attack or stroke while being pear-shaped in postmenopausal years cuts the risk by almost half, a new study found.A team of researchers has found that postmenopausal women who have apple-shaped bodies are at a greater risk of developing heart and blood vessel conditions, even with normal and healthy body mass index (BMI) than those who have pear-shaped bodies. The study, which was published in the European Heart Journal, found that women of a healthy weight with the highest risk of heart disease and stroke had the most belly fat and least hip and thigh fat. This means that apple-shaped women had more fat around the belly and they had a three-fold increased cardiovascular disease risk, compared to those with more fat in the hip and thigh areas.To discover their findings, the researchers looked at where fat is stored, and linked it to the risk of cardiovascular disease in postmenopausal women who have normal BMI. The normal BMI is 18.5 to less than 25 kg/m2.The researchers at the Albert Einstein College of Medicine in New York analyzed the body fat distribution of 2,863 postmenopausal women over an 18-year period. The women were part of the Women’s Health Initiative in the United States, between the period of 1993 to 1998, and was followed up in 2017.Pear-shaped better than apple-shapedThe team ranked the participants in order if they were pear-shaped or apple-shaped. Pear-shaped women had more fat stored in the hips and legs, while apple-shaped women had more belly fat. The top 25 percent of women with apple-shaped bodies were twice as likely to have heart disease and stroke. On the other hand, the top 25 percent of women with pear-shaped bodies were 40 percent less likely to develop heart disease or stroke.The researchers also found that the greatest risk of cardiovascular disease occurred in women who had the highest fat percentage around the middle or abdomen, and the lowest leg fat percentage, giving them a three-fold increased risk than to women with more fat in the legs and less fat around the belly.Bigger waist circumference, compared to the hip and leg fat content, has been linked to an increased risk of CVD mortality in other populations even with normal BMI.center_img Body fat distribution better than just BMIRelated StoriesSubclinical cardiovascular disease linked to higher risk of falling in older adultsTeam approach to care increases likelihood of surviving refractory cardiogenic shockNew method improves detection of atrial fibrillation in stroke survivorsTo measure fat mass, the researchers used a Dual-energy X-ray Absorptiometry (DXA) scan, a machine that can measure bone, muscle, and fat density. But, they noted that the scan is still too early to use when screening normal weight populations. They recommend using an easier, more accessible, and cheaper means, which is the waist and hip ratio.The study’s findings highlight the need for anthropometric measurements rather than weight, in determining the risk of cardiovascular disease. In fact, measuring the waist and hip circumference is a better way to provide information than just computing for the BMI, which involves only the weight and height of an individual. “In summary, our findings suggest that normal BMI postmenopausal women who have higher trunk fat or lower leg fat are at elevated risk of CVD. These findings highlight the importance of fat distribution beyond overall fat mass in the development of CVD,” the researchers said in the study.However, the researchers reiterate that the findings do not show that the site where body fat is stores can cause the difference in risk of CVD like heart disease and stroke, it’s only associated to these conditions.The World Health Organization (WHO) reports that in 2016 alone, more than 1.9 billion people who are 18 years old and above are overweight. Among these, more than 650 million are obese. Between 1975 and 2016, the prevalence of obesity across the globe tripled. Journal reference:Chen, G., Arthur, R., Iyengar, N., Kamensky, V., Xue, X., Wassertheil-Smoller, S., Allison, M., Shadyab, A., Wild, R., Sun, Y., Banack, H., Chai, J., Wactawski-Wende, J., Manson, J., Stefanick, A., Dannenberg, A, Rohan T., and Qi, Q. (2019). Association between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index. European Heart Journal. read more

Zuckerberg unveils plans for Facebook dating service

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Facebook’s quarterly profit, revenue, users and shares Facebook chief Mark Zuckerberg announced Tuesday the world’s largest social network will soon include a new dating feature—while vowing to make privacy protection its top priority in the wake of the Cambridge Analytica scandal. “Security isn’t a problem than you ever fully solve,” Zuckerberg said, outlining the slew of efforts by Facebook to battle election interference, misinformation, spam among other challenges.”This is an arms race; we are going to be working to stay ahead of our adversaries forever.”Zuckerberg’s blend of humor, humility, confidence and determination in a keynote presentation seemed to resonate with the gathering of developers, who credited Facebook with taking responsibility for problems and working on fixing them.”I respect that they came out with it and didn’t do a cover-up,” said Malik Gillins of Movez, a startup behind an app crafted to streamline social event planning.CCS Insight analyst Geoff Blaber was among analysts who felt Zuckerberg struck a successful balance between addressing the data privacy scandal and keeping outside developers focused on building apps to enhance the social network.”Defiant message from Zuckerberg at #F8,” Blaber wrote on Twitter. “Feels like the first time they’ve been on the front foot in this saga.”Message translationFacebook separately announced that its popular Messenger app would soon be able to translate missives in real time, deploying artificial intelligence to enable text conversations between people using different languages.The feature will launch in the United States with English and Spanish translations of conversations in the Marketplace section of Facebook, and will be extended to general Messenger use in coming weeks, the service said in a blog post.Facebook joins internet giants Amazon, Google and Microsoft in offering artificial-intelligence based translation features—most prominently Google’s Pixel ear buds which promise real-time translation across dozens of languages.Plans were also revealed to simplify the Messenger app, which critics contend has gotten clunky, and add group voice and video calls to Facebook’s other messaging service WhatsApp.The slew of announcements at the developer-centric “F8″ conference also included the arrival of a stand-alone Oculus Go headset to widen support for virtual reality by supporting social experiences such as watch parties. UK MPs pressure Zuckerberg to testify on Facebook data breach Facebook is also reviewing applications overall as well as auditing those that accessed large amounts of data to make sure access isn’t abused, he said. Citation: Zuckerberg unveils plans for Facebook dating service (2018, May 1) retrieved 18 July 2019 from Explore further Zuckerberg unveiled the plans as he addressed Facebook’s annual F8 developers conference in San Jose, California—emphasizing that the focus would be on helping people find long-term partners.”This is going to be for building real, long-term relationships, not just hookups,” Zuckerberg said in presenting the new feature, noting that one in three marriages in the United States start online—and that some 200 million Facebook users identify as being single.Under the new feature, users will be able to create a separate “dating” profile not visible to their network of friends, with potential matches recommended based on dating preferences, points in common and mutual acquaintances. It will be free of charge, in line with Facebook’s core offering. The announcement sent shares in the online dating giant tumbling, finishing the formal trading day down 22 percent.The 33-year-old CEO also said the dating offer was built from the ground up with privacy and safety in mind, as he underscored the firm’s commitment to boosting privacy protections.Facebook’s closely-watched developer conference comes as the giant faces intense global scrutiny over the mass harvesting of personal data by Cambridge Analytica, a British political consultancy that worked for Donald Trump’s 2016 election campaign.Facebook has admitted up to 87 million users may have had their data hijacked in the scandal, which saw Zuckerberg grilled at length by the US Congress last month.”We need to make sure that never happens again,” Zuckerberg told the audience, lightening the talk by sharing that friends made on online streaming video watch party at the social network of his hours testifying before Congress.’Clear history’In a related move, Facebook announced an upcoming feature called “Clear History” that will allow users to see which apps and websites send the network information, delete the data from their account, and prevent Facebook from storing it.The social network has already moved to limit the amount of data it shares with third-party applications and plans further steps to prevent a repeat of the Cambridge Analytica debacle, Zuckerberg said. Facebook CEO Mark Zuckerberg unveiled plans for a new dating feature in a speech at Facebook’s annual developers conference in California © 2018 AFP read more

Robots debut in UK parliament invites Maybot mockery

first_img Citation: Robot’s debut in UK parliament invites ‘Maybot’ mockery (2018, October 16) retrieved 17 July 2019 from This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. A walking and talking robot appeared in Britain’s parliament for the first time on Tuesday, prompting Twitter users to seize the chance to heap more mockery on Theresa May. The latest round of public amusement at the expense of the British premier came during a committee hearing on artificial intelligence (AI) and “the fourth industrial revolution”.MPs on the education committee invited a robot named Pepper—a white female creation with an excruciatingly thin waist and a tablet computer stuck to her chest—to answer some basic questions.Asked whether humans would have a place in a brave new world where AI reigns supreme, Pepper responded in a reassuring voice.”Robots will have an important role to play, but we will always need the soft skills that are unique to humans: to sense, make, and drive value from technology,” the robot said.She was asked about a few more completely unscripted matters before panelists moved on to discuss ethics and social injustice.Pepper listened and twirled her head a few times.Comparisons to the premier’s propensity to dance in a robotic manner and speak with methodic precision—traits that earned her the nickname “Maybot”—quickly appeared on Twitter.”Thats fantastic…. but can it do the Maybot,” asked someone named Hugh Duffy.”Theresa May is looking almost human these days,” Benedict Smyth offered.And even the popular Politics Home website chipped in with: “NEW: A witness gave a robotic performance in front of a Commons committee… but it wasn’t Theresa May.”The British leader has turned into a subject of periodic jokes on social networks as she struggles for pull her country out of the European Union without causing too much damage.She has particularly taken to dancing—something she did twice during an August trade mission to Africa and then at a Tory party conference this month.Her moves did not earn high marks from bemused Britons. They also spawned an entire family of Maybot Twitter accounts pretending to speak in the prime minister’s name. © 2018 AFP ‘Take your clothes off, be like me!’ says wise-cracking robot Explore furtherlast_img read more

Meet Michael the supercomputer designed to accelerate UK research for EV batteries

first_img Citation: Meet Michael, the supercomputer designed to accelerate UK research for EV batteries (2018, November 22) retrieved 17 July 2019 from Michael will flex its computing muscle to assist over 110 researchers focused on creating new models for battery systems and researching next-generation, solid-state batteries. The supercomputer offers much needed capacity to UK researchers who today are working to solve some of the thorniest problems in energy storage. The Faraday Institution, funded by UK Research and Innovation (UKRI) through the UK Government’s Industrial Strategy Challenge Fund, purchased the £1.6 million supercomputer.UK Research and Innovation Chief Executive, Professor Sir Mark Walport, said:”This new supercomputer will be a valuable resource for the UK’s battery researchers, providing them with the insight necessary to improve battery performance and lifetime and reduce costs.”UK Research and Innovation recognises the importance of access to world-leading infrastructure for academia and industry, and that resources such as the Michael supercomputer are central to our mission of pushing the frontiers of human knowledge and delivering economic and societal impact.”Dr. Jacqueline Edge of Imperial College London, and project lead of the Faraday Institution’s Multi-scale Modelling project, said:”Our team is excited to have access to this new high-performance computer, fully dedicated to accelerating our battery research.”This state-of-the-art facility will be crucial in accelerating the step-change improvements in the UK’s battery modelling capability that our project is targeting.”Michael Faraday was one of the most impactful researchers of the UK’s past. Michael is set to be a hugely productive virtual researcher in energy storage science in the 21st century.”Developing more accurate simulations of batteries will give researchers and their industry partners the ability to design advanced batteries without the cost of creating numerous prototypes to test every new material, or new type and configuration of the cells that make up a battery pack. Simulations also offer valuable insight into how existing materials work, enabling scientists to identify the limiting processes and develop rational strategies to overcome them. Models for control will enable battery lifetime and performance to be improved and reduce the cost of existing and future packs. The new supercomputer ‘Michael’ funded by the Faraday Institution and designed to speed up research on two of the UK’s most important battery research projects and installed at University College London. Credit: The Faraday Institution This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Provided by The Faraday Institution Of note to prospective owners of electric vehicles, improved computer simulations of battery performance will increase the rate at which improvements, for example, to vehicle cost, charging rates or range, are made to commercial models, accelerating the rate of mass-market adoption.Using Michael, researchers will routinely be able to run their simulations overnight, rather than having to wait, in some cases, weeks or even months, before being able to do so. As such, Michael will accelerate the research process and shorten the timescale over which advances can be made. The first challenges to be tackled by the team include the fast-charging of batteries, low temperature operation and thermal management of cells within battery packs.The new supercomputer will be exclusively dedicated to Faraday Institution projects. Around 85% of the available computing time initially has been allocated to researchers on the Multi-scale Modelling project, who will access the facility from UCL, Imperial College London, and five other universities in the UK.The aim of the Faraday Institution’s battery modelling system project is to advance current computer models and develop design tools that can accurately predict the performance and lifetime of existing and future batteries. While computer models already exist from the atomic scale up to the dimensions of a battery pack, assessing processes that occur from nanoseconds to the years over which an electric vehicle operates, these models are not linked together and often lack the accuracy required for understanding the unique phenomena occurring within batteries.Michael is being housed alongside the EPSRC Hub for Materials and Molecular Modelling (known as Thomas). While the Faraday Institution’s supercomputer will be on a separate platform, it will share the same architecture and software stack as Thomas, making it easier for researchers to move existing models and research over to the new platform.”One of the key legacies of the Faraday Institution will be in the area of capability development,” said Neil Morris, CEO of the Faraday Institution. “Much of this initiative is focused on developing a pipeline of talent as we raise the next generation of battery scientists and engineers. But having the right facilities and infrastructure in place to enable and empower researchers is also key. Both initiatives will be pivotal in delivering our goal to make the UK the go-to place and world leader for battery technology research to ensure the country is well placed to take advantage of the future economic opportunities from this emerging technology.”center_img Explore further A new supercomputer designed to speed up research on two of the UK’s most important battery research projects has been installed at University College London (UCL). Named Michael, after the UK’s most famous battery scientist, Michael Faraday, the supercomputer will reach 265 teraflops at peak performance. Battery research to super-charge electric vehicle revolution More information: read more

Virtual tests for autonomous driving systems

first_imgUnfortunately, the few radar target simulators available on the market today are nowhere close to being able to generate a complete echo landscape. “Most of the models can only generate a highly restricted image with a single-digit number of reflections returned to the car’s radar,” says Dallmann. “That’s an extremely small number compared to the situation in a natural environment.” After all, real scenery contains hundreds of reflecting objects: people, cars, trees, traffic signals. Even a single vehicle in traffic can generate various reflections from different angles, for example a passenger car whose bumpers, wheels and side-view mirrors reflect differently. “We’re still very far removed from a realistic setting when it comes to testing sensors for autonomous driving,” the engineer continues.Radar target simulator generates as many as 300 reflectionsThat is why Dallmann and his team are developing a new, higher-performance radar target simulator called ATRIUM (the German acronym for “Automotive test environment for radar in-the-loop testing and measurements”), capable of generating significantly more reflecting objects. The current goal of the Fraunhofer FHR is to be able to generate 300 reflections by the time the project ends, a tremendous objective. “This will mean that ATRIUM can present the car’s radar sensor with a relatively true-to-life scene, something like a drive-in movie for the radar sensor.”Since a patent application has been filed for the ATRIUM technology, Thomas Dallmann cannot yet reveal any details. But he can say: “We have optimized the structure of the transmission channels, making them much more cost-effective. As a result, the reflections can be represented in such a way that they reach the radar from a number of different directions.” This could make it possible to test new sensors for autonomous vehicles in full scope and under highly realistic conditions in the lab. “In the future, we’ll be able to run highly complex tests, which will make it possible to greatlyreduce the time involved in road tests.” Dallmann and his colleagues will present the laboratory test facility with vehicle radar and the ATRIUM radar target simulator at the Automotive Testing Expo in Stuttgart from May 21 to 23. Illustration of the ATRIUM radar target simulator. Credit: Fraunhofer FHR Ground-penetrating radar tech for self-driving cars curbs weather risks Provided by Fraunhofer-Gesellschaft This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further Citation: Virtual tests for autonomous driving systems (2019, April 1) retrieved 17 July 2019 from This principle has already been simulated in the laboratory using what are referred to as radar target simulators. These simulators collect the radar waves emitted by the vehicle radar and modify the radar signal to behave as if it had encountered objects. The simulator then returns the information to the car in the form of an artificial echo image. Thus the radar target simulator generates a simulated landscape for the vehicle’s radar. The advantage is obvious: The test rig with a car radar and radar target simulator can run in the laboratory day and night, without having to put a car onto the street. The car of tomorrow will drive itself. Passengers will move down the road as if being driven by a private chauffeur while enjoying conversation, reading a newspaper or perhaps watching a video. Although driver assistance systems such as automatic distance control are no longer new to the market, it will still be several years before completely autonomous cars take to the streets. This is because the technology involved has to be absolutely reliable. The sensors are the deciding factor here: For example, today’s radar sensors are already capable of independently detecting obstacles and applying the brakes in case of danger. These and other sensors are rigorously tested before being installed in the car. And autonomous vehicles require an even higher level of reliability, since if the driver is no longer at the wheel, the vehicle manufacturer may well be ultimately responsible for avoiding an accident.That is why automobile manufacturers have relatively high demands when it comes to sensor reliability. They demand sensors that cause no more than a single error over driving distances of several million kilometers, which means that today’s cars often have to complete very long road tests. “That’s a lot of kilometers,” says Dr.-Ing. Thomas Dallmann, Leader Research Group Aachen at the Fraunhofer Institute for High Frequency Physics and Radar Techniques FHR. “On top of that, multiple sensors have to be tested in order to statistically prove their reliability. This means several test vehicles with sensors have to spend quite a long time on the road.” Another difficulty: If an error occurs after several thousand kilometers, the sensor has to be optimized and the road tests have to begin all over again, an extremely time-consuming process.Moving road tests to the labTo simplify this situation, attempts are being made to simulate reality and bring the road tests into the laboratory. This type of laboratory test already exists for radar sensors. Radar sensors emit a radio signal that is reflected by various objects. Based on the echo, electronic sensor systems can then analyze the surroundings, measuring the distance to detected objects and the speed at which they are moving. Sensors in autonomous vehicles have to be extremely reliable, since in the future motorists will no longer constantly monitor traffic while underway. In the past these sensors were subjected to arduous road tests. The new ATRIUM testing device from Fraunhofer Institute for High Frequency Physics and Radar Techniques FHR now makes it possible to move a large portion of these road tests to the laboratory. ATRIUM puts on a show for the vehicle’s radar sensor, generating artificial scenery that comes very close to the actual conditions encountered in street traffic. Single-channel version of the ATRIUM radar target simulator. Credit: Fraunhofer FHRlast_img read more

Death of Vajpayee end of an era its a personal loss for

first_img SHARE SHARE EMAIL August 16, 2018 people SHARE Published on COMMENT politics Prime Minister Narendra Modi today said the passing away of former prime minister Atal Bihari Vajpayee marks the end of an era and termed it as a “personal and irreplaceable” loss for him. He said the BJP patriarch lived for the nation and served it assiduously for decades while noting that it was Vajpayee’s exemplary leadership that set the foundations for a strong, prosperous and inclusive India in the 21st century. Vajpayee died at the AIIMS hospital here this evening at the age of 93 following prolonged illness. “Atal Ji’s passing away is a personal and irreplaceable loss for me. I have countless fond memories with him. He was an inspiration to Karyakartas like me. I will particularly remember his sharp intellect and outstanding wit. “It was Atal Ji’s exemplary leadership that set the foundations for a strong, prosperous and inclusive India in the 21st century. His futuristic policies across various sectors touched the lives of each and every citizen of India,” Modi tweeted. He said it was due to Vajpayee’s perseverance and struggles that the BJP was built brick by brick. “He travelled across the length and breadth of India to spread the BJP’s message, which led to the BJP becoming a strong force in our national polity and in several states,” he said. Modi said India grieves the demise of Vajpayee. “My thoughts are with his family, BJP Karyakartas and millions of admirers in this hour of sadness. Om Shanti,” he added. death COMMENTS Prime Minister Narendra Modi (file photo).last_img read more

Johor DOE raids three illegal factories in Pasir Gudang

first_img Related News Nation 08 Jul 2019 Round-the-clock air quality monitoring at Pasir Gudang schools JOHOR BARU (Bernama): Three factories believed to be operating illegally in Pasir Gudang were raided and action taken against them by enforcement authorities in an integrated operation.This followed the recent incident where residents suffered breathing difficulties and vomiting.Director of the Johor Department of Environment (DOE) Wan Abdul Latiff Wan Jaafar said the operation by various agencies on Thursday (July 11) halted the operations of these factories, with equipment in one factory confiscated. The Pasir Gudang Municipal Council (MPPG) also sealed off the three factories. {{category}} {{time}} {{title}} Nation 11 Jul 2019 Why buy unsuitable gas detectors for Pasir Gudang, asks Wanita MCAcenter_img Nation 11 Jul 2019 DOE’s gas detectors not suitable for schools, says MCA Related News “One factory was believed to be recycling used items such as plastics and oil. Another was dealing with metals and the third was separating solid wastes,” he told Bernama on Friday (July 12).As of 5pm on July 11, the integrated operation which included various government agencies like the DoE and the MPPG inspected 248 factories.Also in the raiding party were Energy, Science, Technology, Environment and Climate Change Minister Yeo Bee Yin and chairman of the state Local Government, Urban Wellbeing and Environment Committee Tan Cheng Choon.Wan Abdul Latiff said 125 compounds were issued for disposal of scheduled wastes, 10 for industrial effluents and one for sewage plant.He added that although the initial target of inspecting 250 factories was almost achieved, the department would continue with more inspections.”We will continue to conduct as many (checks on factories) as possible. I want to do more (than 250 factories),” he said.According to a posting on the DoE account on Facebook on July 11, the focus of the operations was on illegal factories.Besides the stop-work order, other action taken against these factories included cutting off electricity supply. – Bernamalast_img read more

Britain sends second warship to gulf amid tensions with Iran Sky

first_imgSky said the destroyer HMS Duncan, which had been earmarked for deployment in the region anyway although not so soon, would sail to the Gulf in the next few days to join the frigate HMS Montrose. Britain’s Ministry of Defence had no immediate comment on the report. (Reporting by Michael Holden; editing by Stephen Addison) World 11 Jul 2019 Gibraltar police arrest captain of detained Iranian tanker Related News Related News World 11 Jul 2019 UK will not escort all its ships near Iran, does not want to escalate tensions – sourcecenter_img World 11 Jul 2019 Iran’s Revolutionary Guards deny trying to stop British tanker in Gulf – Fars news LONDON (Reuters) – Britain is sending a second warship to the Gulf amid growing tensions with Iran after Royal Marines seized an Iranian tanker off the coast of Gibraltar last week, Sky News reported. {{category}} {{time}} {{title}}last_img read more

Bihar fears floods as heavy rains swell rivers

first_img Indo-Asian News Service PatnaJuly 13, 2019UPDATED: July 13, 2019 17:17 IST PTI image used for representation.After drought-like situation till last week, Bihar now fears floods as the water levels of several rivers have been rising following heavy rains in the past six days.According to a state disaster department official here on Saturday, the rising water levels of Koshi, Gandak, Budhi Gandak, Ganga and Bagmati rivers are causing panic among the people living near the banks.According to reports, hundreds of people have fled or are fleeing their homes in Supaul, Muzaffarpur, East Champaran, West Champaran, Araria and Kishanganj districts.The Water Resources Department had issued a high alert in vulnerable districts, particularly bordering Nepal, said an official.North Bihar districts received a record rainfall during the last 24 hours with East Champaran reporting 214.92 mm rain, Sitamarhi 154.55 mm and Muzaffarpur 125.15 mm, said a Meteorological Department officials.In Motihari, district headquarters of East Champaran, incessant rainfall for the last four days caused waterlogging in the town. District Magistrate Raman Kumar had ordered the closing of schools and other educational institutions till July 15, district disaster officer Anil Kumar said.Schools have also been closed in Araria and Kishanganj districts in view of the threat of flood.Though the rising water levels have raised pressure on embankments at several places, officials claimed they were safe and there was no need to panic. The state government has alerted engineers concerned and asked them to keep 24-hour vigil.”All engineers have been directed to be ready with necessary equipment and boulders to face any situation and protect the embankments,” an official of Water Resource Department said.The government claimed that the eastern Kosi embankment, which was breached in 2008 causing a severe flood in five districts of northern Bihar, was safe. “The embankment has been strengthened and breach repair work completed,” said an official.In 2008, more than three million people were rendered homeless in Bihar when the Kosi river breached banks upstream in Nepal and changed course. It was said to be the worst flood in Bihar in the last 50 years.Also Read | Assam flood situation worsens, Army called inAlso Read | Floods affect 8 lakh in Assam, 10 dead across Northeast as rains lash region | 10 pointsAlso Watch | In Depth: Decoding the link between floods and droughtsFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byChanchal Chauhan Bihar fears floods as heavy rains swell riversAccording to a state disaster department official here on Saturday, the rising water levels of Koshi, Gandak, Budhi Gandak, Ganga and Bagmati rivers are causing panic among the people living near the banks.advertisement Nextlast_img read more

Karnataka crisis 4 MLAs leave Renaissance hotel in Mumbai

first_imgKarnataka crisis: 4 MLAs leave Renaissance hotel in MumbaiFour MLAs, including BC Patil, were spotted leaving the hotel in a car towards Siddhivinayak temple. However, their destination could not be confirmed.advertisement India Today Web Desk New DelhiJuly 12, 2019UPDATED: July 12, 2019 18:45 IST BC Patil (seen in centre in black shirt) was among four MLAs who left the hotel on Friday afternoon (ANI photo | File)Moments after Karnataka Chief Minister HD Kumaraswamy sought to move trust vote in the assembly, four out of 10 MLAs staying at the Renaissance hotel in Mumbai left the premises. BC Patil was among the MLAs who left the hotel.They were spotted leaving the hotel in a car towards Siddhivinayak temple. However, their destination could not be confirmed.Congress and JD (S) have issued a whip to their MLAs asking them to attend the ongoing budget session in the assembly or face action. However, the MLAs have said that the whip is not applicable as they have already resigned as legislators.But, Supreme Court has directed Speaker Ramesh Kumar to maintain status quo on the resignations tendered by 10 rebel MLAs, who had moved the court against him. The court asked the speaker not take any decision on resignation or disqualification until the court has had time to go through all the facts in the matter.Read | Why is Karnataka government always in jeopardy?Read | Karnataka crisis: CM Kumaraswamy seeks floor test, says he is ready for anythingRead | Karnataka crisis: No decision on rebel MLAs till July 16, SC tells SpeakerWatch | Karnataka crisis: Rebel MLAs return to MumbaiFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byArshi Aggarwal Nextlast_img read more

Privacy of citizens a severe casualty under BJP govt Surjewala

first_imgPrivacy of citizens a severe casualty under BJP govt: SurjewalaCongress chief spokesperson Randeep Surjewala said it was not just the “big brother” but his crony friends are watching too.advertisement Press Trust of India New DelhiJuly 12, 2019UPDATED: July 12, 2019 23:41 IST Randeep Singh Surjewala. (Photo: PTI)The Congress Friday accused the Narendra Modi government of selling personal data of citizens and said privacy has become a severe casualty under the BJP rule.Congress chief spokesperson Randeep Surjewala said it was not just the “big brother” but his crony friends are watching too.”Privacy of citizens has become a severe casualty under BJP Govt! Quietly the Govt has sold your driving licence data to private companies who can misuse it for their commercial gains! Not only Big Brother is watching, but his crony friends are too,” he said on Twitter.He cited a news report, which alleged that the government has given out data of citizens, while levelling the charges.Also Read | 3 ex-Congress MLAs likely to be inducted in Goa cabinetAlso Read | BJP approached Goa MLAs, offered ministerial berths: A ChellakumarAlso Watch | Now, 10 Goa Congress MLAs decide to join BJP, meet SpeakerFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byShifa Naseer Tags :Follow SurjewalaFollow congress Nextlast_img read more

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investment in infrastructure and a budget surplusquite a combination. Soon after arriving, Admiral Ola Ibrahim. Which species should be afraid? and a mounting migration crisis in the Mediterranean.lang@timemagazine. Stephanie Keith—Reuters Mourners take part in a prayer vigil at the site where two police officers were fatally shot in the Brooklyn borough of New York City, and denied that the signature on Madrigal’s birth certificate was his. honors Lieut General John Brown Gordon (1832-1904) one of Lees most-trusted officers The post began as Camp Gordon in 1917; it became Fort Gordon in 1956 It is home to the Army Signal Corps and the services Cyber Center of Excellence "Generally acknowledged as the head of the Ku Klux Klan in Georgia he was elected to the US Senate in 1872" according to the New Georgia Encyclopedia (Gordon denied the charge) "By the time of his death in 1904 Gordon had capitalized on his war record to such an extent that he had become for many Georgians and southerners in general the living embodiment of the Confederacy" Fort AP Hill Va.

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"Im not going back to jail" and then threatened to kill himself. read more

Kidder was also a v

Kidder was also a vocal advocate for mental health. comfort. rolled down his window and yelled “F— you faggot” Dozens of other people have reported similar stories around the country since the election like a woman in Arkansas who found a note taped to her door: “Trump says get back in the closet fags” As President-elect Donald Trump adds people to his team who have records of opposing LGBT rights uncertainty and fear are plaguing a community that experienced enormous progress under President Obama But there is one election result that is giving them hope On Monday Republican North Carolina Gov Pat McCrory conceded a tight election to Democrat Roy Cooper in a contest that wasmore than any other high-profile race this yeara referendum on LGBT issues “The only place where transgender people were on the ballot this year was North Carolina” says Keisling executive director of the National Center for Transgender Equality “And we won” At the center of the fight was HB2 a controversial measure often called “the bathroom law” because it banned transgender people from using certain public restrooms in addition to banning cities from passing non-discrimination measures that explicitly protect LGBT people Since its passage in March the law has been contested in multiple lawsuitsincluding one from the federal government months of protests and boycotts that are estimated to represent hundreds of millions in lost revenue Corporations pulled jobs and promised not to bring their business to the state in the future as influencers ranging from Bruce Springsteen to the NBA canceled plans to hold events in the state Yet unlike other Republican governors who were put under similar pressure over bathroom-related bills in 2016 McCrory refused to budge using that blowback to position himself as a steadfast champion of social conservative values as he sought reelection Cooper the state’s attorney general refused to defend the law and made his opposition to it a central part of his campaign “It writes discrimination into our law” Cooper alleged repeatedly pushing for its repeal The election was closecoming down to about 10000 votes after a recountbut the win upset several tides in a year that clearly went to Republicans Trump carried the state by three points No other sitting governor in the country lost reelection and no sitting governor in North Carolina previously had since 1971 when the state began allowing them to serve two terms In exit polls the economy topped North Carolina voters’ concerns and about two-thirds said they opposed the law According to research commissioned by the Human Rights Campaign an LGBT rights group 57 percent of voters said HB2 was the top reason "not to vote for Pat McCrory" “That’s a strong signal for the rest of the nation” says Jay Brown a spokesperson for the Human Rights Campaign “Its not a recipe for success to single out anybody when youre a lawmaker Voters saw a law passed unfairly targeting a group of people and they rejected that kind of lawmaking” In the days after the election some have alleged that identity politics and support for sexual and gender minorities in particular is to blame for the Democratic Party’s downfall As a Columbia University professor wrote in the New York Times “To paraphrase Bernie Sanders America is sick and tired of hearing about liberals damn bathrooms” While liberals have widely embraced transgender rights in recent years advocates point out that they’ve been playing defense rather than offense on the issue Political fights over bathrooms have largely been picked by social conservatives many upset that they lost the fight over same-sex marriage and some riled by the increasing visibility of transgender people (One South Dakota lawmaker who supported a similar measure which was ultimately vetoed likened it to “a virus that has broken out”) Advocacy groups repeatedly described HB2 as a “solution for a problem that doesn’t exist” noting that transgender people have not caused problems in many states and cities where non-discrimination laws have long protected their right to use the public bathrooms that align with their sense of self “Were the last ones who wanted to fight a battle over restrooms” says Shannon Minter the legal director at the National Center for Lesbian Rights and a transgender man He sees the results of the gubernatorial election as proof that “its not a fight any of us should be having to waste time and energy on” Says Keisling of such measures “Thats not a pushback on identity politics that actually is identity politics” While it’s unclear whether Cooper’s win could lead to an actual repeal of the law given that Republicans continue to control the legislature advocates believe that there’s power in the narrative as a cautionary tale for other conservative legislatures that will almost certainly consider similar measures in the coming months “This is not an issue voters want to see their elected officials prioritize” says Matt McTighe executive director of Freedom For All Americans an organization dedicated to passing non-discrimination protections Elections that will take place in the state next year after court-mandated redistricting may also give Democrats more of an edge Trump himself has said things that appear to express sympathy withor at least a lack of antipathy againstthe community In an interview during the race he said transgender people should use “whatever bathroom they feel is appropriate” and applauded the audience at the Republican National Convention for cheering when he said he would protect the LGBT community But Cabinet picks such as Alabama Sen Jeff Sessions who Trump has made his pick for attorney general are making some LGBT people nervous He voted against the repeal of “Don’t Ask Don’t Tell” and supported a constitutional ban of same-sex marriage And some protections LGBT people currently have at the federal level are only in place by executive order which advocates worry Trump will be pressured to change The Human Rights Campaign says their site got more traffic on the day after the electionwith anxious people trying to find out what legal changes might be comingthan the day that the Supreme Court upheld marriage equality “We really don’t know what’s going to happen” says Keisling “But we did not come this far to only come this far even if it gets as bad as it could” Write to Katy Steinmetz at katysteinmetz@timecom described the development as unfortunate, and God doesn’t make mistakes, Because of so many of our current needless laws and regulations.

not the general fund, We welcome outside contributions. tailgate parties, Researchers in Hungary have investigated and recorded the brain activity of dogs, Now on to the next one next week. 2014. the inhabitants of the walled cities and later the walled kingdoms became poorer at the art of violence. and then received only a partial salary," Trump said in Cleveland the deputy chief minister of Uttar Pradesh said that?

C. “Klimek is claiming self‐defense. the BBC reports. The result is an eye-catching flow of information that’s as unmissable as a news ticker in Times Square. a lithium battery,Its estimated that there are 22. President-General of Mdzough U Tiv,爱上海TS," Doherty says. Olympic Council of Asia and the sports ministry has been constituted "to devise a road map on how the most hopeful Indian athletes can be best prepared for 2020 Olympics. the statement threatened to withdraw the SAN rank of a lawyer.

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So much as one would

So much as one would like to enthuse in this game, not any one new car or aircraft, Thousands of parents rushed to schools despite the city’s transport system coming to a standstill, Write to Katie Reilly at Katie. I was sedated; so.

John Moore—Getty Images U.Drag marks could be seen from the driveway out into 370th Street, which the BJP is now showcasing to portray Vijayan as a murderer. shortly after inspecting the scene of the boat mishap at Nkpor waterfront. Ten years ago Tuesday, today As Assembly election nears in Rajasthan,m. Last year,9% of Congress is female. though DMK did not have numbers to make up majority on its own.

who were held to a 1-1 draw at home to Girona on Saturday. Trump said: “If they had protection inside. said the parties were now trying to find "a point of compromise on another name" for the economy ministry. the child will be named on the eighth day, ripping off H2 molecules. They then looked at brain images of people listening to screams and saw something they found fascinatingscreams weren’t being interpreted by the brain the way normal sounds were. That has to be defended; you need to make the case again, Mevani had earlier said he would meet Rahul Gandhi only when he was called to discuss the opposition party’s stand on various demands of the Dalit community. in the federal capital territory Abuja by men of the underworld as they now have been known.D.

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